Probing the Principles of Cell Signaling AND Behavior

 

We study the fundamental principles that cells use to make essential decisions, like whether to grow or to die. We focus on understanding how cells process signals in their environment through time and space, how proper signal processing drives cell decisions, and how improper signal processing may underlie disease. We specialize in using light-activatible tools that allow us to probe living cells in real-time with high precision. We anticipate that our work will reveal new insights for cellular engineering and control for various therapeutic and industrial applications. 

The only way to find out what will happen when a complex system is disturbed is to disturb the system, not merely to observe it passively
— Fred Mosteller and John Tukey, paraphrasing George Box